SCHEMBL7754714

SCHEMBL7754714

CCCO[SiH](OCCC)C(N)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.38
EPHX1 P07099 1/20 0.33
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28419183 0.70 EPHX1 (0.38) SHBGEPHX1TP53LMNA
SCHEMBL17592723 0.68 SHBG (0.39) SHBGEPHX1TP53KDM4EGMNN
SCHEMBL16287560 0.66 SHBG (0.44) SHBGEPHX1TP53KDM4EGMNN
SCHEMBL16286822 0.66 SHBG (0.44) SHBGEPHX1TP53KDM4EGMNN
SCHEMBL2700537 0.66 SHBG (0.44) SHBGEPHX1TP53LMNA
SCHEMBL7925352 0.66 CYP1A2 (0.33) SHBG
SCHEMBL11853870 0.66 SHBG (0.44) SHBGEPHX1TP53KDM4EGMNN
SCHEMBL3275670 0.66 ALDH1A1 (0.36) SHBG
SCHEMBL1314192 0.66 CYP1A2 (0.33) SHBG
SCHEMBL19356784 0.64 SHBG (0.35) SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP disclosed
US-5556730-A Charge injection barrier for positive charging organic photoconductor HEWLETT-PACKARD COMPANY (US) 1996-09-17 US disclosed
US-5476604-A Crosslinked binder of polyvinyl alcohol HEWLETT-PACKARD COMPANY (US) 1995-12-19 US disclosed
EP-0667562-A2 Charge injection barrier for positive charging organic photoconductor Hewlett-Packard Company (US) 1995-08-16 EP disclosed