Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753891 | 0.82 | ABCB1 (0.57) | MAPK1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL7753943 | 0.81 | MEN1 (0.58) | MAPK1ALDH1A1GAALMNAMAPT | |
| SCHEMBL6546897 | 0.80 | MEN1 (0.52) | MAPK1ALDH1A1POLBKDM4EPKM | |
| SCHEMBL6812211 | 0.79 | CASP1 (0.57) | ALDH1A1POLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7752909 | 0.77 | MAPT (0.68) | MAPK1ALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6546175 | 0.77 | PKM (0.55) | ALDH1A1LMNAPKM | |
| SCHEMBL31541226 | 0.77 | MAPT (0.58) | ALDH1A1POLBCYP1A2CYP2C19TP53 | |
| SCHEMBL16624687 | 0.77 | ALDH1A1 (0.55) | MAPK1ALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7754219 | 0.76 | MEN1 (0.51) | — | |
| SCHEMBL14916767 | 0.75 | SMN1; SMN2 (0.68) | MAPK1ALDH1A1POLBSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068176-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | Jomaa, Hassan (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-2000027803-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | JOMAA, HASSAN (DE) | 2000-05-18 | — | — | WO | disclosed |