Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5604299 | 0.74 | ALDH1A1 (0.35) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL6554047 | 0.74 | GPR3 (0.34) | — | |
| Hydrochloric Acid SCHEMBL3112670 | 0.73 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL3127468 | 0.72 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| SCHEMBL6434682 | 0.72 | — | — | |
| SCHEMBL7626398 | 0.71 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| SCHEMBL6438619 | 0.71 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL3107898 | 0.71 | MAPT (0.30) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3677053 | 0.71 | — | — | |
| SCHEMBL7626392 | 0.71 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092730-A1 | PROCESS FOR PRODUCING OLEFIN POLYMER AND OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2001-04-18 | — | — | EP | disclosed |