Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869337 | 0.88 | MTNR1A (0.55) | TP53MAPTSMN1; SMN2MTNR1ATHRB | |
| SCHEMBL8869526 | 0.88 | AIMP2 (0.39) | TP53MAPTSMN1; SMN2KDM1APOLB | |
| SCHEMBL8867913 | 0.85 | MTNR1A (0.47) | TP53MAPTSMN1; SMN2MTNR1ATSHR | |
| SCHEMBL10222548 | 0.83 | TP53 (0.59) | TP53MAPTSMN1; SMN2MTNR1ATHRB | |
| SCHEMBL8868012 | 0.83 | MTNR1A (0.45) | TP53MTNR1ATSHRHSD17B10 | |
| SCHEMBL7137898 | 0.81 | THRB (0.46) | TP53MAPTSMN1; SMN2THRBKDM1A | |
| SCHEMBL8867009 | 0.80 | HTR1A (0.37) | TP53MAPTSMN1; SMN2MTNR1AKDM1A | |
| SCHEMBL6613340 | 0.78 | PTPN1 (0.43) | KDM1A | |
| SCHEMBL8950321 | 0.78 | CSNK2A1 (0.50) | MAPTSMN1; SMN2THRBPOLBGAA | |
| SCHEMBL8168864 | 0.78 | ESR2 (0.47) | MAPTTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721947-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | EP | disclosed |
| CN-1061653-C | Novel alkylated (hetero) cyclic compounds, process for their prepn. and pharmaceutical compositions contg. same | ADIR (FR) | 2001-02-07 | — | — | CN | disclosed |
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| CN-1134938-A | Novel alkylated (hetero) cyclic compounds, process for their prepn. and pharmaceutical compositions contg. same | ADIR (FR) | 1996-11-06 | — | — | CN | disclosed |
| EP-0721947-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |