Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756353 | 0.80 | TP53 (0.49) | MTNR1AKDM1ATP53MAPTSMN1; SMN2 | |
| SCHEMBL8868639 | 0.77 | CDK2 (0.33) | HTR1AMTNR1ACYP2D6KDM1AMTNR1B | |
| SCHEMBL8869337 | 0.77 | MTNR1A (0.55) | HTR1AMTNR1ATP53MTNR1BMAPT | |
| SCHEMBL8867913 | 0.75 | MTNR1A (0.47) | HTR1AMTNR1ATP53MTNR1BMAPT | |
| SCHEMBL7137898 | 0.73 | THRB (0.46) | KDM1ATP53MAPTSMN1; SMN2 | |
| SCHEMBL11342932 | 0.73 | CYP2A6 (0.50) | HTR1ATP53HTR1DHTR2C | |
| SCHEMBL8950321 | 0.73 | CSNK2A1 (0.50) | HTR1AMAPTSMN1; SMN2GAAHTR1D | |
| SCHEMBL6613340 | 0.73 | PTPN1 (0.43) | HTR1ASLC6A4KDM1AHTR1DHTR2C | |
| SCHEMBL8168864 | 0.73 | ESR2 (0.47) | HTR1AMAPTHTR1DHTR2C | |
| SCHEMBL8868012 | 0.73 | MTNR1A (0.45) | HTR1AMTNR1ASLC6A4TP53MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |