Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867913 | 0.92 | MTNR1A (0.47) | MTNR1ATP53MAPTSMN1; SMN2HTR1A | |
| SCHEMBL8868012 | 0.89 | MTNR1A (0.45) | MTNR1ATP53HTR1AHTR1DHTR2C | |
| SCHEMBL7756353 | 0.88 | TP53 (0.49) | MTNR1ATP53MAPTSMN1; SMN2THRB | |
| SCHEMBL7137898 | 0.78 | THRB (0.46) | TP53MAPTSMN1; SMN2RAB9ATHRB | |
| SCHEMBL8867009 | 0.77 | HTR1A (0.37) | MTNR1ATP53MAPTSMN1; SMN2HTR1A | |
| SCHEMBL8869526 | 0.76 | AIMP2 (0.39) | TP53MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8950321 | 0.75 | CSNK2A1 (0.50) | MAPTSMN1; SMN2HTR1AHTR1DHTR2C | |
| SCHEMBL6613340 | 0.75 | PTPN1 (0.43) | HTR1AHTR1DHTR2C | |
| SCHEMBL8168864 | 0.75 | ESR2 (0.47) | MAPTHTR1AHTR1DHTR2CRAB9A | |
| SCHEMBL11342932 | 0.75 | CYP2A6 (0.50) | TP53HTR1AHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |