Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932087 | 0.85 | EPHX1 (0.66) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9402833 | 0.84 | L3MBTL1 (0.60) | MAPTALDH1A1LMNAHTTEPHX2 | |
| SCHEMBL8028212 | 0.82 | KMT2A (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4683057 | 0.79 | MAPT (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1943274 | 0.78 | KDR (0.55) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27280311 | 0.78 | HSD17B10 (0.59) | MAPTALDH1A1LMNAEPHX2EPHX1 | |
| SCHEMBL31198183 | 0.78 | HSD17B10 (0.59) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5674663 | 0.78 | HSD17B10 (0.59) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10877968 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7751082 | 0.75 | GSTO1 (0.56) | MAPTALDH1A1LMNAHTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704539-B1 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0603954-B1 | Immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0603953-B1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5736335-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5705357-A | DETECTING PEROXIDASE; SENSITIVITY, LOW BACKGROUND; MEDICAL DIAGNOSIS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5641635-A | Dry elements, test devices, test kits and methods for chemiluminescent detection of analytes using peroxidase-labeled reagents | EASTMAN KODAK COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0704539-A2 | Chemiluminescent reagent and assay using a substituted acetanilide for light generation | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5372931-A | Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5372932-A | Peroxidase-labeled immunoreactant; stabiliztion with a 4-hydroxy or 4-alkoxyarylacetamide | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| EP-0603953-A1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603954-A2 | Analytical element and immunoassay using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1994-06-29 | — | — | EP | disclosed |