Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 6/20 | 0.33 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757145 | 0.95 | CES2 (0.40) | LMNAMAPK1HTTMAPTCES2 | |
| SCHEMBL7761145 | 0.89 | CYP2C9 (0.34) | LMNAMAPK1HTTMAPTCYP2C9 | |
| SCHEMBL7760148 | 0.81 | CES2 (0.42) | CES2CES1FAAHMEN1CYP1A2 | |
| SCHEMBL7757123 | 0.77 | CES2 (0.39) | CES2CES1FAAHMEN1CYP1A2 | |
| SCHEMBL7757124 | 0.77 | CES2 (0.39) | LMNACES2CES1FAAHMEN1 | |
| SCHEMBL7757136 | 0.72 | CES2 (0.47) | CES2CES1FAAHMEN1CYP1A2 | |
| SCHEMBL7761197 | 0.72 | CES2 (0.47) | CES2CES1FAAHMEN1CYP1A2 | |
| SCHEMBL7763686 | 0.71 | CES2 (0.35) | MAPTCES2CES1FAAHMEN1 | |
| SCHEMBL7761183 | 0.69 | CES2 (0.33) | CES2CES1FAAHMEN1CYP1A2 | |
| SCHEMBL14795141 | 0.69 | THRA (0.42) | LMNACYP2C9HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |