Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763703 | 0.95 | CES2 (0.40) | CES2FAAHBCHEEPHX1CES1 | |
| SCHEMBL7763686 | 0.93 | CES2 (0.35) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7761147 | 0.89 | LMNA (0.32) | EPHX1HSD17B10 | |
| SCHEMBL7761964 | 0.88 | CES2 (0.42) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7760136 | 0.82 | LMNA (0.33) | HSD17B10 | |
| SCHEMBL27224617 | 0.70 | CYP1A2 (0.36) | EPHX1CYP1A2 | |
| SCHEMBL7757158 | 0.69 | LMNA (0.37) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7760148 | 0.69 | CES2 (0.42) | CES2FAAHEPHX1CES1MEN1 | |
| SCHEMBL29623086 | 0.68 | CYP1A2 (0.37) | EPHX1MEN1CYP1A2KMT2AFDPS | |
| SCHEMBL28333420 | 0.68 | NAAA (0.41) | BCHEEPHX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |