SCHEMBL7757737

SCHEMBL7757737

O=S(=O)(c1ccccc1[Bi](c1ccccc1S(=O)(=O)N(CCO)CCO)c1ccccc1S(=O)(=O)N(CCO)CCO)N(CCO)CCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
MMP1 P03956 2/20 0.38
MMP7 P09237 2/20 0.38
MMP8 P22894 2/20 0.38
MMP12 P39900 2/20 0.38
MMP13 P45452 2/20 0.38
VCAM1 P19320 1/20 0.36
HTT P42858 1/20 0.35
PRKCA P17252 2/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 1/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758285 0.79 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2ANPC1GAA
SCHEMBL7759472 0.79 HTT (0.49) SMN1; SMN2MEN1KMT2ANPC1HTT
SCHEMBL20930300 0.77 GAA (0.48) SMN1; SMN2MEN1KMT2AALOX5APFEN1
SCHEMBL9683547 0.77 SMN1; SMN2 (0.46) SMN1; SMN2MEN1KMT2AALOX5APFEN1
SCHEMBL15915823 0.77 L3MBTL1 (0.54) SMN1; SMN2MEN1KMT2AALOX5APFEN1
SCHEMBL15924800 0.76 ALOX5AP (0.52) SMN1; SMN2MEN1KMT2AALOX5APFEN1
SCHEMBL231935 0.72 VCAM1 (0.56) SMN1; SMN2MEN1KMT2AMMP1MMP8
SCHEMBL3622125 0.72 SMN1; SMN2 (0.67) SMN1; SMN2MEN1KMT2ANPC1GAA
SCHEMBL9511076 0.70 SMN1; SMN2 (0.42) SMN1; SMN2MEN1KMT2AALOX5APFEN1
SCHEMBL967857 0.69 VCAM1 (0.52) SMN1; SMN2MEN1KMT2AMMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5730953-A RADIOGRAPHIC CONTRAST MEDIUM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US claimed
EP-0716091-B1 TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE NISSAN CHEMICAL IND LTD (JP) 2001-03-21 EP disclosed
US-5730953-A RADIOGRAPHIC CONTRAST MEDIUM NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0716091-A1 TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1996-06-12 EP disclosed