Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757737 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL7757769 | 0.74 | VCAM1 (0.36) | SMN1; SMN2VCAM1NPC1SERPINE1KDM4E | |
| SCHEMBL2835133 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL6676536 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL6257441 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL8157313 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL218536 | 0.69 | SMN1; SMN2 (0.68) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL11686046 | 0.69 | VCAM1 (0.63) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL11685605 | 0.69 | VCAM1 (0.59) | SMN1; SMN2VCAM1GAANPC1MMP1 | |
| SCHEMBL3622125 | 0.69 | SMN1; SMN2 (0.67) | SMN1; SMN2VCAM1GAANPC1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716091-B1 | TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5730953-A | RADIOGRAPHIC CONTRAST MEDIUM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0716091-A1 | TRIS(SUBSTITUTED PHENYL)BISMUTH DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |