SCHEMBL7758359

SCHEMBL7758359

NC(=O)N(C(=O)c1c(Cl)cccc1Cl)c1ccc(F)cc1F

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
KMT2A Q03164 1/20 0.44
RORC P51449 14/20 0.42
MAPK14 Q16539 2/20 0.38
PBRM1 Q86U86 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11218595 0.87 PARP1 (0.41) GAALMNAPKMKMT2ARORC
SCHEMBL7760757 0.86 RORC (0.41) RORCPBRM1
SCHEMBL7760781 0.84 RORC (0.43) GAALMNAPKMKMT2ARORC
SCHEMBL28905451 0.78 FSCN1 (0.44) GAARORC
SCHEMBL28504601 0.78 ALDH1A1 (0.40) GAALMNARORC
SCHEMBL28498195 0.76 ALDH1A1 (0.41) GAALMNAPKMKMT2ARORC
SCHEMBL7760787 0.76 RORC (0.45) GAAKMT2ARORCPBRM1
SCHEMBL10719934 0.76 RORC (0.41) GAARORCPBRM1
SCHEMBL7753768 0.76 RORC (0.42) GAARORCPBRM1
SCHEMBL7757536 0.76 RORC (0.41) GAALMNAPKMKMT2ARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed