SCHEMBL7760757

SCHEMBL7760757

NC(=O)N(C(=O)c1c(Cl)cccc1Cl)c1ccc(I)cc1F

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RORC P51449 15/20 0.41
PBRM1 Q86U86 1/20 0.34
MAP2K1 Q02750 3/20 0.34
CA2 P00918 1/20 0.34
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
TYK2 P29597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758359 0.86 GAA (0.44) RORCPBRM1
SCHEMBL7760781 0.79 RORC (0.43) RORCPBRM1
SCHEMBL7754454 0.77 ALDH1A1 (0.39) RORC
SCHEMBL7759310 0.76 RORC (0.40) RORCPBRM1
SCHEMBL28905451 0.76 FSCN1 (0.44) RORC
SCHEMBL28504601 0.76 ALDH1A1 (0.40) RORCJAK2TYK2
SCHEMBL28498195 0.74 ALDH1A1 (0.41) RORC
SCHEMBL7753768 0.74 RORC (0.42) RORCPBRM1
SCHEMBL7760787 0.74 RORC (0.45) RORCPBRM1
SCHEMBL10719934 0.74 RORC (0.41) RORCPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed