Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068415 | 0.86 | RECQL (0.55) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL8444546 | 0.84 | ALDH1A1 (0.62) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL6068479 | 0.84 | DRD2 (0.54) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL6068501 | 0.81 | ADRA1A (0.55) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL7758406 | 0.81 | HTR1A (0.59) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL6068170 | 0.79 | DRD2 (0.52) | DRD2ADRA1ADRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6313945 | 0.77 | RECQL (0.52) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL6068410 | 0.77 | DRD2 (0.50) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL7758410 | 0.76 | HTR1A (0.53) | DRD2ADRA1ADRD3MEN1KMT2A | |
| SCHEMBL8442569 | 0.75 | HTR1A (0.55) | DRD2ADRA1ADRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087954-A1 | CYCLOALKYL-SUBSTITUTED ARYL-PIPERAZINES, PIPERIDINES AND TETRAHYDROPYRIDINES AS SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-04-04 | — | — | EP | claimed |
| WO-1999065887-A1 | CYCLOALKYL-SUBSTITUTED ARYL-PIPERAZINES, PIPERIDINES AND TETRAHYDROPYRIDINES AS SEROTONERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-23 | — | — | WO | claimed |