Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.69 |
| ▸ | MMP3 | P08254 | 8/20 | 0.69 |
| ▸ | MMP7 | P09237 | 3/20 | 0.69 |
| ▸ | MMP2 | P08253 | 8/20 | 0.66 |
| ▸ | MMP9 | P14780 | 6/20 | 0.66 |
| ▸ | MMP14 | P50281 | 4/20 | 0.66 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | HPN | P05981 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806856 | 1.00 | MMP1 (0.69) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7765086 | 0.90 | MMP1 (0.55) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7762136 | 0.82 | MMP1 (1.00) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL9284470 | 0.80 | MMP2 (1.00) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7762157 | 0.75 | MMP2 (0.58) | MMP1MMP3MMP2 | |
| SCHEMBL7763096 | 0.71 | MMP3 (0.80) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7451414 | 0.71 | MMP1 (0.71) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7761307 | 0.71 | MMP1 (0.46) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7762316 | 0.70 | MMP2 (0.75) | MMP1MMP3MMP7MMP2MMP9 | |
| SCHEMBL7763149 | 0.70 | MMP1 (0.61) | MMP1MMP3MMP7MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | claimed |
| EP-1098662-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004892-A2 | COADMINISTRATION OF ACAT AND MMP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROTIC LESIONS | WARNER-LAMBERT COMPANY (US) | 2000-02-03 | — | — | WO | disclosed |