Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667921 | 0.81 | CES2 (0.36) | CES2CES1 | |
| Bromide SCHEMBL733561 | 0.79 | CES2 (0.34) | CES2CES1 | |
| SCHEMBL13741967 | 0.78 | CYP17A1 (0.52) | CYP11B2CYP17A1CYP11B1NOTUMHSD17B1 | |
| SCHEMBL7758944 | 0.77 | BCL2L1 (0.39) | NOTUM | |
| SCHEMBL7766400 | 0.77 | CYP11B2 (0.48) | CYP11B2CYP17A1CYP11B1NOTUMHSD17B1 | |
| SCHEMBL11833556 | 0.74 | ALDH1A1 (0.50) | — | |
| SCHEMBL19665044 | 0.74 | CYP11B1 (0.50) | CYP11B2CYP17A1CYP11B1NOTUMHSD17B1 | |
| SCHEMBL11837452 | 0.72 | CYP1A2 (0.48) | NOTUMKIF11LMNA | |
| SCHEMBL7769653 | 0.72 | ALOX5 (0.50) | CYP11B2CYP17A1CYP11B1NOTUMHSD17B1 | |
| SCHEMBL2552043 | 0.72 | CYP11B1 (0.48) | CYP11B2CYP17A1CYP11B1NOTUMHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696591-B1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHINETSU CHEMICAL CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5514824-A | Process for preparing silacyclohexane-base liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0696591-A1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |