Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421827 | 0.81 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL3845082 | 0.78 | HCAR2 (0.34) | TSHRLMNAALDH1A1 | |
| SCHEMBL12920504 | 0.77 | TSHR (0.50) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL7064188 | 0.77 | ABCB11 (0.30) | TSHR | |
| SCHEMBL1420928 | 0.75 | ALDH1A1 (0.45) | TSHRLMNAALDH1A1 | |
| SCHEMBL7059527 | 0.75 | DGAT1 (0.39) | KMT2ALMNAALDH1A1 | |
| SCHEMBL7064864 | 0.74 | CYP4F2 (0.43) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL801638 | 0.73 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL7065716 | 0.69 | NPC1 (0.35) | TSHR | |
| SCHEMBL7059507 | 0.69 | TSHR (0.37) | TSHRALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066077-A1 | USE OF 4-OXORETINOL AND DERIVATIVES THEREOF IN COSMETIC PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | disclosed |