Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PDE6D | O43924 | 2/20 | 0.60 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.60 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.60 |
| ▸ | RORC | P51449 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547289 | 0.90 | ALDH1A1 (0.60) | ALDH1A1PDE6DALDH2ALDH3A1RORC | |
| SCHEMBL29412125 | 0.81 | TP53 (0.72) | ALDH1A1PDE6DALDH2ALDH3A1RORC | |
| SCHEMBL6475293 | 0.80 | ALDH1A1 (0.68) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL28503579 | 0.80 | ALDH1A1 (0.63) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL29411888 | 0.78 | TP53 (0.70) | ALDH1A1PDE6DALDH2ALDH3A1RORC | |
| SCHEMBL229828 | 0.76 | ALDH1A1 (1.00) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL17537500 | 0.76 | TP53 (0.52) | RORCTP53MAPTBRD4 | |
| SCHEMBL28505411 | 0.75 | DRD2 (0.66) | ALDH1A1PDE6DALDH2ALDH3A1RORC | |
| SCHEMBL6475362 | 0.74 | ALDH1A1 (0.74) | ALDH1A1PDE6DALDH2ALDH3A1TP53 | |
| SCHEMBL29412013 | 0.74 | ALDH1A1 (0.73) | ALDH1A1PDE6DALDH2ALDH3A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579827-B1 | METHOD OF PREPARING 2-ARYLBENZIMIDAZOLE 5-SULPHONIC ACIDS | MERCK PATENT GMBH (DE) | 2001-04-18 | — | — | EP | disclosed |
| US-5473079-A | Process for preparing 2-arylbenzimidazole-5-sulfonic acids | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |