Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754588 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HTTTDP1POLBAPEX1 | |
| SCHEMBL668868 | 0.87 | PLA2G2A (0.50) | TDP1TSHRPLA2G2ATP53PLA2G4B | |
| SCHEMBL17186650 | 0.85 | THRA (0.40) | HTTTDP1TSHRPLA2G2ATP53 | |
| SCHEMBL8100381 | 0.84 | PLA2G2A (0.41) | HTTTSHRPLA2G2ATP53PLA2G4B | |
| SCHEMBL8106324 | 0.84 | PLA2G2A (0.41) | HTTTSHRPLA2G2ATP53PLA2G4B | |
| SCHEMBL17186600 | 0.84 | PLA2G2A (0.37) | HTTTDP1TSHRPLA2G2ATP53 | |
| SCHEMBL8106646 | 0.79 | CYSLTR2 (0.35) | ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL8102311 | 0.79 | CYSLTR2 (0.35) | ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL5587043 | 0.74 | PLA2G2A (0.44) | TDP1TSHRPLA2G2ATP53PLA2G4B | |
| SCHEMBL5589712 | 0.74 | PLA2G2A (0.44) | TDP1TSHRPLA2G2ATP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754675-B1 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 2001-03-21 | — | — | EP | disclosed |
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |
| EP-0754675-A2 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 1997-01-22 | — | — | EP | disclosed |