Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761417 | 0.80 | HTR1A (0.50) | HTR1AHTR2CDRD2ADRB2ADRB1 | |
| SCHEMBL7756735 | 0.79 | DRD4 (0.47) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL7761668 | 0.77 | MARS1 (0.48) | HTR1AHTR2CDRD2PGRADRB2 | |
| SCHEMBL9437757 | 0.76 | HTR1A (0.48) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL7760532 | 0.76 | HTR1A (0.50) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL7761677 | 0.76 | PDE3B (0.56) | HTR1AHTR2CPDE3BPDE3ADRD2 | |
| SCHEMBL9164783 | 0.75 | HTR1A (0.47) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL7761660 | 0.75 | CXCR4 (0.44) | HTR1AHTR2CPDE3BPDE3ALMNA | |
| SCHEMBL8948245 | 0.75 | SIGMAR1 (0.52) | HTR1AHTR2CMAPT | |
| SCHEMBL1324801 | 0.75 | HTR1A (0.49) | HTR1AHTR2CMAPTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |