Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761417 | 0.84 | HTR1A (0.50) | ADRB2ADRB1DRD2ADRA1DSIGMAR1 | |
| SCHEMBL7756735 | 0.83 | DRD4 (0.47) | HTR1AHTR2C | |
| SCHEMBL9618249 | 0.80 | CYP1A2 (0.61) | MARS1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7761677 | 0.80 | PDE3B (0.56) | ADRB2ADRB1DRD2ADRA1DHTR1A | |
| SCHEMBL7760532 | 0.80 | HTR1A (0.50) | HTR1AHTR2C | |
| SCHEMBL7759828 | 0.77 | HTR1A (0.42) | ADRB2ADRB1DRD2HTR1AHTR2C | |
| SCHEMBL8948102 | 0.76 | SIGMAR1 (0.63) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL1325447 | 0.75 | HTR1A (0.49) | DRD2HTR1AHTR2CPGR | |
| SCHEMBL9684052 | 0.74 | HTR1A (0.48) | DRD2HTR1AHTR2CPGR | |
| SCHEMBL9437757 | 0.73 | HTR1A (0.48) | DRD2SIGMAR1HTR1AHTR2CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |