Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761417 | 0.89 | HTR1A (0.50) | CHRM2HTR1AHTR2CHDAC3HDAC4 | |
| SCHEMBL7761677 | 0.87 | PDE3B (0.56) | CHRM2HTR1AHTR2CPDE3BPDE3A | |
| SCHEMBL7760532 | 0.84 | HTR1A (0.50) | DRD4ALDH1A1HTR1AHTR2CMAPT | |
| SCHEMBL7761668 | 0.83 | MARS1 (0.48) | HTR1AHTR2C | |
| SCHEMBL7759828 | 0.79 | HTR1A (0.42) | ALDH1A1HTR1AHTR2CMAPTPDE3B | |
| SCHEMBL9437757 | 0.78 | HTR1A (0.48) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL9686038 | 0.77 | ALDH1A1 (0.51) | ALDH1A1PKMHTR1AHTR2CMAPT | |
| SCHEMBL9685780 | 0.77 | HTR1A (0.50) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL8948181 | 0.76 | SIGMAR1 (0.51) | CHRM2HTR1AHTR2CMAPT | |
| SCHEMBL9658547 | 0.76 | HTR1A (0.48) | ALDH1A1PKMHTR1AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |