Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.54 |
| ▸ | STK39 | Q9UEW8 | 2/20 | 0.51 |
| ▸ | SMO | Q99835 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761587 | 0.79 | GPR27 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4TMPRSS4 | |
| SCHEMBL8469626 | 0.78 | CHRNB2 (0.48) | CHRNB2CHRNB4CHRNA3CHRNA4TMPRSS4 | |
| SCHEMBL649648 | 0.77 | PPARG (0.49) | TMPRSS4STK39SMOTP53MEN1 | |
| SCHEMBL15568158 | 0.76 | PPARG (0.48) | TMPRSS4STK39SMOTP53MEN1 | |
| Potassium SCHEMBL15568160 | 0.76 | PPARG (0.48) | TMPRSS4STK39SMOTP53MEN1 | |
| SCHEMBL574119 | 0.75 | P2RX1 (0.59) | STK39MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL8460416 | 0.75 | AURKA (0.47) | TMPRSS4STK39SMOTP53MEN1 | |
| SCHEMBL8469266 | 0.74 | SMO (0.56) | SMOTP53MEN1KMT2ARAB9A | |
| SCHEMBL28017780 | 0.72 | SMO (0.55) | SMOTP53MEN1KMT2ARAB9A | |
| SCHEMBL1648370 | 0.72 | GPR27 (0.53) | TMPRSS4SMOTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070189-A1 | METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS | UNILEVER PLC (GB) | 2001-09-27 | — | — | WO | disclosed |