Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3124936 | 0.98 | ALOX5 (0.53) | ALOX5OPRM1OPRD1EPHX1KDM5A | |
| SCHEMBL7760755 | 0.81 | ALOX5 (0.67) | ALOX5EPHX1 | |
| SCHEMBL194060 | 0.76 | NTRK2 (0.36) | — | |
| SCHEMBL11094217 | 0.73 | OPRM1 (0.41) | ALOX5OPRM1OPRD1KDM5AKDM4C | |
| SCHEMBL2843504 | 0.72 | NTRK2 (0.34) | — | |
| SCHEMBL11317847 | 0.72 | NTRK2 (0.38) | — | |
| SCHEMBL21359084 | 0.71 | OPRM1 (0.42) | ALOX5OPRM1OPRD1 | |
| SCHEMBL13711905 | 0.69 | SIGMAR1 (0.38) | ALOX5 | |
| SCHEMBL20723734 | 0.69 | GPR84 (0.35) | — | |
| SCHEMBL8600806 | 0.69 | ALDH1A1 (0.43) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |