Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 8/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761183 | 0.95 | CES2 (0.33) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7761964 | 0.93 | CES2 (0.42) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7761147 | 0.88 | LMNA (0.32) | HSD17B10EPHX1 | |
| SCHEMBL7763686 | 0.88 | CES2 (0.35) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7760136 | 0.80 | LMNA (0.33) | HSD17B10 | |
| SCHEMBL28333420 | 0.73 | NAAA (0.41) | CYP1A2EPHX1BCHE | |
| SCHEMBL20683522 | 0.71 | ARG1 (0.51) | FDPS | |
| SCHEMBL4830272 | 0.70 | CES2 (0.61) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7757145 | 0.70 | CES2 (0.40) | CES2LPAR1LPAR3FAAHCES1 | |
| Hydrochloric Acid SCHEMBL3239446 | 0.69 | CES2 (0.59) | CES2LPAR1LPAR3FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |