Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | PPIA | P62937 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPIF | P30405 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18889365 | 0.91 | KMT2A (0.52) | KMT2AMEN1PPIAALDH1A1PPIF | |
| SCHEMBL9574658 | 0.82 | HSD17B10 (0.60) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL10917701 | 0.82 | ALOX5 (0.54) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4452103 | 0.81 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1MAPTRAB9A | |
| SCHEMBL4944452 | 0.79 | KMT2A (0.62) | KMT2AMEN1PPIAALDH1A1PPIF | |
| SCHEMBL7900646 | 0.79 | MAOB (0.55) | KMT2AMEN1PPIAALDH1A1MAPT | |
| SCHEMBL6730910 | 0.79 | PPIA (0.55) | KMT2AMEN1PPIAHTTPPIF | |
| SCHEMBL4699514 | 0.79 | CYP19A1 (0.60) | KMT2AMEN1PPIAALDH1A1HTT | |
| SCHEMBL2081746 | 0.78 | MAPT (0.71) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL11021047 | 0.78 | MAPT (0.62) | KMT2AALDH1A1HTTMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1315962-A | Novel method for synthesizing Exochelins | KEYSTONE BIOMEDICAL INC (US) | 2001-10-03 | — | — | CN | claimed |
| EP-1105416-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | Keystone Biomedical, Inc. (US) | 2001-06-13 | — | — | EP | claimed |
| US-6063919-A | ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) | KEYSTONE BIOMEDICAL, INC. (US) | 2000-05-16 | — | — | US | claimed |
| WO-2000009547-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | KEYSTONE BIOMEDICAL, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| CN-1315962-A | Novel method for synthesizing Exochelins | KEYSTONE BIOMEDICAL INC (US) | 2001-10-03 | — | — | CN | disclosed |
| EP-1105416-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | Keystone Biomedical, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6063919-A | ESTERIFICATION OF O-DEPROTECTED DIBENZYL EXOCHELIC ACID WITH BENZYL EPI-COBACTIN, HYDROGENOLYTICALLY REMOVING THE THREE BENZYL GROUPS TO FORM EXOCHELIN 786SM(R) | KEYSTONE BIOMEDICAL, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| WO-2000009547-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF EXOCHELINS | KEYSTONE BIOMEDICAL, INC. (US) | 2000-02-24 | — | — | WO | disclosed |