Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363575 | 0.77 | PI4KA (0.37) | TRPA1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6993509 | 0.65 | LIMK1 (0.42) | RPS6KA3HPGDHSD17B10ALDH1A1CXCR2 | |
| SCHEMBL21242832 | 0.59 | SMN1; SMN2 (0.53) | HPGDHSD17B10ALDH1A1CXCR2SMN1; SMN2 | |
| SCHEMBL28955037 | 0.57 | PNP (0.46) | HPGDHSD17B10ALDH1A1KDM4ETHRB | |
| Thiazolopyrimidine SCHEMBL1703410 | 0.57 | RPS6KA3 (0.52) | RPS6KA3HPGDHSD17B10ALDH1A1CXCR2 | |
| SCHEMBL18076190 | 0.55 | ADORA2A (0.56) | — | |
| SCHEMBL2642790 | 0.54 | HSD17B10 (0.39) | HPGDHSD17B10ALDH1A1CXCR2 | |
| SCHEMBL22993546 | 0.54 | ALDH1A1 (0.55) | HPGDHSD17B10ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL18909173 | 0.52 | — | — | |
| SCHEMBL6003749 | 0.52 | NOS1 (0.38) | HPGDHSD17B10ALDH1A1CXCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001073438-A1 | RICIN INHIBITORS AND METHODS FOR USE THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-10-04 | — | — | WO | claimed |
| WO-2001073438-A1 | RICIN INHIBITORS AND METHODS FOR USE THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-10-04 | — | — | WO | disclosed |