Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772184 | 0.88 | F2 (0.64) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL5368249 | 0.80 | CA2 (0.43) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL16443971 | 0.80 | CA2 (0.47) | CA2SMN1; SMN2PDPK1 | |
| SCHEMBL17080150 | 0.80 | CA2 (0.43) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL4240715 | 0.80 | CA2 (0.47) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL7769099 | 0.79 | F2 (0.57) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL5368246 | 0.78 | CA2 (0.46) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL9671990 | 0.78 | TDP1 (0.48) | TP53THRATHRB | |
| SCHEMBL10413400 | 0.77 | CA2 (0.66) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL427617 | 0.75 | CA2 (0.64) | F2TMPRSS4TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689929-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2024-05-31 | — | — | CN | disclosed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-12 | — | — | US | disclosed |
| EP-3151817-B1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | SCRIPPS RESEARCH INST (US) | 2021-03-03 | — | — | EP | disclosed |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-24 | — | — | US | disclosed |
| CN-111689929-A | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-09-22 | — | — | CN | disclosed |
| US-10765645-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-08 | — | — | US | disclosed |
| CN-106659700-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-07-10 | — | — | CN | disclosed |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-31 | — | — | US | disclosed |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2017-07-13 | — | — | US | disclosed |
| EP-3151817-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | The Scripps Research Institute (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188120-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
| EP-0740690-B1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | SYNGENTA LTD (GB) | 2001-06-20 | — | — | EP | disclosed |
| US-5739299-A | GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES | ZENECA LIMITED (GB) | 1998-04-14 | — | — | US | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, NAF1, CYP2S1 | F2 181/4885TMPRSS4 3833/4885TP53 2986/4885 |
| US-10765645-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | HAX1, CYP2F1, CYP4X1 | F2 245/4885TMPRSS4 3783/4885TP53 3014/4885 |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | QSOX1, YBX1, SFXN1 | F2 257/4885TMPRSS4 2921/4885TP53 879/4885 |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | HAX1, CYP2F1, CYP4X1 | F2 245/4885TMPRSS4 3783/4885TP53 3014/4885 |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, CYP2S1, NAF1 | F2 153/4885TMPRSS4 3690/4885TP53 3033/4885 |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | CYP2F1, CYP2S1, NAF1 | F2 153/4885TMPRSS4 3690/4885TP53 3033/4885 |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | CYP2F1, NAF1, CYP2S1 | F2 181/4885TMPRSS4 3833/4885TP53 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.