SCHEMBL7769099

SCHEMBL7769099

O=S(=O)(F)c1ccc(CBr)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.57
TMPRSS4 Q9NRS4 2/20 0.57
TSHR P16473 2/20 0.57
TP53 P04637 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CA2 P00918 8/20 0.37
CA1 P00915 7/20 0.37
CA9 Q16790 6/20 0.37
CA12 O43570 5/20 0.37
CA7 P43166 5/20 0.37
CA4 P22748 4/20 0.37
CA6 P23280 4/20 0.37
CA5A P35218 4/20 0.37
CA14 Q9ULX7 4/20 0.37
CA5B Q9Y2D0 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11411795 0.94 F2 (0.52) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL7772184 0.82 F2 (0.64) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL1148233 0.80 HTR6 (0.47) TSHRTRPA1ALDH1A1CES2CES1
SCHEMBL11574176 0.79 TSHR (0.56) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL7764249 0.79 F2 (0.60) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL11700692 0.78 F2 (0.59) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL8996770 0.78 TSHR (0.42) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL15212213 0.77 PSIP1 (0.41) F2TMPRSS4TSHRTP53CYP1A2
SCHEMBL240747 0.76 ENPP2 (0.50) TSHRTRPA1ALDH1A1CA2
SCHEMBL16066056 0.76 CA2 (0.61) F2TMPRSS4TSHRTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939927-A SuFEx click reaction-based cyclic carbonate monomer, polymer and preparation method thereof 苏州大学 2021-06-11 CN claimed
CN-120648689-A Covalent nucleic acid aptamer and application thereof 徐州医科大学 2025-09-16 CN disclosed
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
CN-119876163-A Nucleoside monomer containing exogenous functional group chemical modification and covalent nucleic acid aptamer containing nucleoside monomer 浙江工业大学 2025-04-25 CN disclosed
CN-111689929-B Sulfur fluoride (VI) compound and preparation method thereof 斯克里普斯研究所 2024-05-31 CN disclosed
CN-117916242-A SHP2 inhibitors and uses thereof 治纳辅医药科技有限公司 2024-04-19 CN disclosed
CN-117843642-A Difunctional compound and application thereof 麦科萨药业(苏州)有限公司 2024-04-09 CN disclosed
CN-117700564-A Modified peptide material targeting SARS-CoV-2 Omikovia mutant S protein RBD and preparation method thereof 清华大学 2024-03-15 CN disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
WO-2023221234-A1 IN VITRO SCREENING METHOD FOR COVALENT INHIBITOR AND USE THEREOF 清华大学 2023-11-23 WO disclosed
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2018-11-06 US disclosed
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE 2017-07-13 US disclosed
EP-3151817-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF The Scripps Research Institute (US) 2017-04-12 EP disclosed
WO-2015188120-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
WO-2015188060-A1 FLUOROSULFONYL sEH INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
WO-2015188060-A1 FLUOROSULFONYL sEH INHIBITORS THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed
EP-0740690-B1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF SYNGENTA LTD (GB) 2001-06-20 EP disclosed
US-5739299-A GOOD WET FASTNESS AND LIGHT FASTNESS PROPERTIES ZENECA LIMITED (GB) 1998-04-14 US disclosed
EP-0740690-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-06 EP disclosed
WO-1995020014-A1 MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF CYP2F1, NAF1, CYP2S1 F2 181/4885TMPRSS4 3833/4885TSHR 409/4885
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR F2 929/4885TMPRSS4 975/4885TSHR 7/4885
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof CYP2F1, NAF1, CYP2S1 F2 181/4885TMPRSS4 3833/4885TSHR 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.