SCHEMBL7764283

SCHEMBL7764283

CC(C)c1cc(C(C)C)c(Br)c(C(C)C)c1.[MgH2]

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.48
GABRB2 P47870 2/20 0.48
FABP4 P15090 5/20 0.46
FABP3 P05413 2/20 0.46
FABP5 Q01469 1/20 0.45
GABRB1 P18505 3/20 0.41
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALDH1A1 P00352 1/20 0.32
SOAT2 O75908 1/20 0.30
MYC P01106 1/20 0.30
SOAT1 P35610 1/20 0.30
MAP2K3 P46734 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339679 0.97 GABRA1 (0.50) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL8169296 0.95 GABRA1 (0.48) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL20681258 0.78 GABRA1 (0.64) GABRA1GABRB2FABP4FABP3GABRB1
SCHEMBL11399190 0.77 GABRA1 (0.42) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL14156687 0.77 GABRA1 (0.38) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL31517134 0.76 GABRA1 (0.42) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL3440745 0.76 GABRA1 (0.50) GABRA1GABRB2FABP4FABP3FABP5
SCHEMBL28454010 0.74 GABRA1 (0.58) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL19507083 0.74 GABRA1 (0.58) GABRA1GABRB2GABRB1CA1CA2
SCHEMBL4712954 0.74 GABRA1 (0.52) GABRA1GABRB2GABRB1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12410271-B1 CO2 chemical reaction viscosity-increasing type polymer surfactant for gas channeling control during CO2 flooding in offshore heavy oil reservoirs, preparation method therefor and use thereof CHINA UNIVERSITY OF PETROLEUM (EAST CHINA) (CN) 2025-09-09 US disclosed
US-12297311-B2 Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-13 US disclosed
EP-3642250-B1 BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-18 EP disclosed
US-12122862-B2 Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-22 US disclosed
CN-117794644-A Iron-catalyzed metathesis polymerization of olefins 耶达研究与发展有限公司 2024-03-29 CN disclosed
CN-117279981-A Method for producing polysiloxazanes and for producing amino-functional polyorganosiloxanes using same 美国陶氏有机硅公司 2023-12-22 CN disclosed
CN-117003783-A Organic compound and application thereof 清华大学 2023-11-07 CN disclosed
CN-110809586-B Biaryl phenoxy group IV transition metal catalysts for olefin polymerization 陶氏环球技术有限责任公司 2023-06-27 CN disclosed
US-20220169756-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-02 US disclosed
US-20220025085-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2022-01-27 US disclosed
EP-3935091-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY Dow Global Technologies LLC (US) 2022-01-12 EP disclosed
US-11168161-B2 Biaryl phenoxy group IV transition metal catalysts for olefin polymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-09 US disclosed
WO-2020185494-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-17 WO disclosed
US-20200157254-A1 BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYERMIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-21 US disclosed
EP-3642250-A1 BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-04-29 EP disclosed
WO-2018236996-A1 BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-27 WO disclosed
EP-1097116-A1 ASYMMETRIC METATHESIS REACTIONS INVOLVING ACHIRAL AND MESO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 EP disclosed
WO-2000002834-A1 ASYMMETRIC METATHESIS REACTIONS INVOLVING ACHIRAL AND MESO SUBSTRATES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220025085-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY TRMT1, GFPT1, BCAT1 GABRA1 2993/4885GABRB2 2296/4885FABP4 904/4885
US-12122862-B2 Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability TRMT1, GFPT1, BCAT1 GABRA1 2993/4885GABRB2 2296/4885FABP4 904/4885
US-11168161-B2 Biaryl phenoxy group IV transition metal catalysts for olefin polymerization PPOX, LIG4, PARG GABRA1 2812/4885GABRB2 2370/4885FABP4 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.