Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776746 | 0.92 | LMNA (0.60) | MAPK1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL776355 | 0.91 | NPC1 (0.59) | MAPK1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL774893 | 0.91 | NPC1 (0.59) | MAPK1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL776594 | 0.87 | KCNJ11 (0.63) | MAPK1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL776464 | 0.84 | SMN1; SMN2 (0.59) | LMNANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL775262 | 0.79 | EP300 (0.61) | MAPK1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL776816 | 0.78 | EP300 (0.64) | MAPK1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL778783 | 0.78 | EP300 (0.64) | MAPK1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9815030 | 0.75 | EP300 (0.60) | MAPK1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30665216 | 0.75 | MAPK1 (0.55) | MAPK1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |