Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770270 | 0.89 | KIF11 (0.41) | KIF11KCNH2AOC3 | |
| SCHEMBL7772520 | 0.89 | KIF11 (0.43) | KIF11LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL7772503 | 0.85 | KIF11 (0.39) | KIF11LMNASMN1; SMN2 | |
| SCHEMBL7772528 | 0.79 | KIF11 (0.47) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8607101 | 0.76 | ALDH1A1 (0.44) | KIF11AOC3 | |
| SCHEMBL7772513 | 0.76 | TDP1 (0.43) | LMNAHTTKMT2AMEN1AOC3 | |
| SCHEMBL7764652 | 0.71 | CASR (0.44) | KIF11KCNH2LMNAKMT2AMEN1 | |
| SCHEMBL7147740 | 0.70 | KIF11 (0.61) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28440590 | 0.70 | KIF11 (0.54) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL28076975 | 0.70 | KIF11 (0.54) | KIF11KCNH2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |