Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766761 | 0.84 | CYP3A4 (0.40) | CYP3A4CYP1A2CYP2D6PRMT1GRM2 | |
| SCHEMBL7765797 | 0.73 | KMT2A (0.38) | CYP3A4CYP1A2CYP2D6PRMT1 | |
| SCHEMBL9557980 | 0.70 | CTSV (0.38) | CYP3A4GRM2 | |
| SCHEMBL7766815 | 0.69 | CRBN (0.43) | CYP3A4DAOGRM2IDO1 | |
| SCHEMBL7764976 | 0.66 | TNKS (0.32) | — | |
| SCHEMBL7764873 | 0.66 | CYP2C19 (0.41) | CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7764884 | 0.66 | CRBN (0.36) | IDO1 | |
| SCHEMBL7765815 | 0.66 | CYP3A4 (0.38) | CYP3A4CYP1A2CYP2D6PRMT1GRM2 | |
| SCHEMBL7766827 | 0.64 | CYP2C19 (0.39) | CYP3A4CYP1A2CYP2D6GRM2 | |
| SCHEMBL7765770 | 0.63 | CYP2C19 (0.38) | CYP3A4CYP1A2CYP2D6GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |