Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765830 | 1.00 | CYP1A2 (0.37) | CYP1A2MAPK1SMN1; SMN2POLBMAPT | |
| SCHEMBL7764161 | 0.88 | ALDH1A1 (0.38) | SMN1; SMN2POLBKMT2AMEN1KDM4E | |
| SCHEMBL7764155 | 0.88 | ALDH1A1 (0.38) | SMN1; SMN2POLBKMT2AMEN1KDM4E | |
| SCHEMBL6943418 | 0.79 | BCHE (0.39) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6943422 | 0.79 | BCHE (0.39) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7764173 | 0.79 | BCHE (0.39) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7764176 | 0.79 | BCHE (0.39) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6986468 | 0.78 | BCHE (0.38) | SMN1; SMN2 | |
| SCHEMBL7977210 | 0.78 | MEN1 (0.35) | POLBKMT2AMEN1 | |
| SCHEMBL5679507 | 0.78 | CPB2 (0.37) | POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |