Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764161 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CTSKPOLBMMP3MMP9 | |
| SCHEMBL7765827 | 0.88 | CYP1A2 (0.37) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7765830 | 0.88 | CYP1A2 (0.37) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6946023 | 0.77 | CTSK (0.33) | CTSKKMT2ASMN1; SMN2USP2 | |
| SCHEMBL6945400 | 0.77 | CTSK (0.33) | CTSKKMT2ASMN1; SMN2USP2 | |
| SCHEMBL7977209 | 0.76 | MEN1 (0.35) | CTSKPOLBMEN1KMT2A | |
| SCHEMBL5679507 | 0.76 | CPB2 (0.37) | CTSKPOLBMEN1KMT2A | |
| SCHEMBL7977210 | 0.76 | MEN1 (0.35) | CTSKPOLBMEN1KMT2A | |
| SCHEMBL15015766 | 0.75 | CTSL (0.39) | ALDH1A1CTSKPOLBMEN1KMT2A | |
| SCHEMBL7518207 | 0.75 | CTSL (0.39) | ALDH1A1CTSKPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |