Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 5/20 | 0.41 |
| ▸ | MMP13 | P45452 | 5/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765858 | 1.00 | MMP2 (0.41) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL7078766 | 0.84 | MMP2 (0.36) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL7368800 | 0.77 | MMP1 (0.37) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL7221727 | 0.77 | MMP2 (0.37) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL7078769 | 0.76 | MMP2 (0.36) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL7765827 | 0.74 | CYP1A2 (0.37) | — | |
| SCHEMBL7765830 | 0.74 | CYP1A2 (0.37) | — | |
| SCHEMBL7215123 | 0.73 | MMP2 (0.35) | MMP2MMP9MMP1MMP13MMP8 | |
| SCHEMBL5679507 | 0.73 | CPB2 (0.37) | — | |
| SCHEMBL7977210 | 0.73 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |