Malonic Acid

Malonic Acid

SCHEMBL7765984

CCCCCCCCCCCC(C)N(Cc1ccc(CN(C(C)CCCCCCCCCCC)C(C)CCCCCCCCCCC)cc1)C(C)CCCCCCCCCCC.O=C(O)CC(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 7/20 0.43
S1PR2 O95136 6/20 0.43
S1PR3 Q99500 6/20 0.42
ALDH1A1 P00352 1/20 0.41
CNR2 P34972 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
S1PR4 O95977 3/20 0.39
GPR84 Q9NQS5 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL7768273 0.91 S1PR1 (0.48) S1PR1S1PR2S1PR3ALDH1A1THRA
Acetic Acid SCHEMBL7764900 0.91 THRA (0.42) S1PR1S1PR2S1PR3ALDH1A1CNR2
Adipic Acid SCHEMBL7764425 0.90 FFAR4 (0.51) S1PR1S1PR2S1PR3ALDH1A1GPR84
Malonic Acid SCHEMBL7764459 0.89 CNR2 (0.43) CNR2
Lactic Acid SCHEMBL7768220 0.88 GPR84 (0.45) S1PR1S1PR2S1PR3THRATHRB
Cadaverine Tartrate SCHEMBL7764537 0.87 GPR84 (0.44) S1PR1S1PR2S1PR3THRATHRB
Hydrochloric Acid SCHEMBL7760906 0.86 THRA (0.37) ALDH1A1THRATHRB
Hydrochloric Acid SCHEMBL8720967 0.86 THRA (0.37) ALDH1A1THRATHRB
Hydrochloric Acid SCHEMBL8719708 0.86 THRA (0.37) ALDH1A1THRATHRB
Hydrochloric Acid SCHEMBL7764492 0.86 THRA (0.37) ALDH1A1THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825175-B1 Quaternary ammonium disinfectant NICCA CHEMICAL CO (JP) 2001-06-13 EP disclosed
EP-0825175-A1 Quaternary ammonium disinfectant NICCA CHEMICAL CO., LTD. (JP) 1998-02-25 EP disclosed