Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL7768220 | 0.93 | GPR84 (0.45) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Acetic Acid SCHEMBL7764900 | 0.90 | THRA (0.42) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Cadaverine Tartrate SCHEMBL7764905 | 0.89 | CSNK1E (0.40) | GPR84FFAR1ACE2CSNK1E | |
| Gluconic Acid SCHEMBL7764369 | 0.88 | PDE4A (0.44) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Malonic Acid SCHEMBL7765984 | 0.87 | S1PR1 (0.43) | GPR84S1PR2S1PR1S1PR3S1PR4 | |
| Succinic Acid SCHEMBL7768273 | 0.87 | S1PR1 (0.48) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Cadaverine Tartrate SCHEMBL7764354 | 0.86 | CSNK1E (0.42) | GPR84FFAR1ACE2CSNK1E | |
| Adipic Acid SCHEMBL7764425 | 0.86 | FFAR4 (0.51) | GPR84FFAR1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL7764492 | 0.85 | THRA (0.37) | THRATHRBMAPTLCKCSNK1E | |
| Hydrochloric Acid SCHEMBL8720967 | 0.85 | THRA (0.37) | THRATHRBMAPTLCKCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |