Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.49 |
| ▸ | RARB | P10826 | 11/20 | 0.49 |
| ▸ | RARG | P13631 | 10/20 | 0.49 |
| ▸ | RXRB | P28702 | 9/20 | 0.49 |
| ▸ | RXRG | P48443 | 7/20 | 0.49 |
| ▸ | RARA | P10276 | 9/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218543 | 0.81 | CYP3A4 (0.58) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL2195789 | 0.77 | CYP3A4 (0.61) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL5367554 | 0.75 | CYP3A4 (0.56) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL7143184 | 0.74 | CYP3A4 (0.54) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL6324909 | 0.72 | HSD17B3 (0.43) | CYP3A4ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL10647869 | 0.72 | RARB (0.50) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL10647875 | 0.72 | RARB (0.50) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL8733241 | 0.72 | RARB (0.83) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL19072651 | 0.71 | CYP3A4 (0.63) | RXRARARBRARGRXRBRXRG | |
| SCHEMBL2195224 | 0.70 | RXRA (0.66) | RXRARARBRARGRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | disclosed |