Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.43 |
| ▸ | ESR1 | P03372 | 5/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318579 | 0.88 | HSD17B3 (0.46) | HSD17B3ESR1ESR2SMN1; SMN2HPGD | |
| SCHEMBL814927 | 0.87 | CES2 (0.52) | ESR1ESR2SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL818007 | 0.76 | CES2 (0.56) | ESR1SMN1; SMN2HPGDL3MBTL1LMNA | |
| SCHEMBL27488403 | 0.75 | HTR7 (0.61) | HSD17B3ESR1ESR2HPGDALDH1A1 | |
| SCHEMBL815083 | 0.74 | PTGS2 (0.57) | ESR1ALDH1A1PTGS2CES2CES1 | |
| SCHEMBL3989195 | 0.72 | ALDH1A1 (0.48) | SMN1; SMN2HPGDMEN1ALDH1A1LMNA | |
| SCHEMBL815888 | 0.72 | CES2 (0.56) | ESR1LMNAPTGS2CES2CES1 | |
| SCHEMBL7766041 | 0.72 | RXRA (0.49) | SMN1; SMN2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10343596 | 0.71 | MAOB (0.42) | SMN1; SMN2L3MBTL1MEN1ALDH1A1LMNA | |
| SCHEMBL814748 | 0.71 | CES2 (0.58) | L3MBTL1MEN1LMNAMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906226-B2 | Hydroxymethyl-substituted polyfunctional phenols | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-06-14 | — | — | US | disclosed |