Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MTAP | Q13126 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764955 | 0.96 | EHMT2 (0.38) | EHMT2ALDH1A1LMNAPSMD14GPR55 | |
| SCHEMBL7765809 | 0.84 | EHMT2 (0.42) | EHMT2ALDH1A1LMNAPSMD14GPR55 | |
| SCHEMBL7767480 | 0.75 | CRBN (0.40) | EHMT2ALDH1A1LMNAPSMD14GPR55 | |
| SCHEMBL7769361 | 0.74 | CYP1A2 (0.40) | EHMT2ALDH1A1KMT2AMEN1HCRTR1 | |
| SCHEMBL7765770 | 0.73 | CYP2C19 (0.38) | ALDH1A1LMNACYP2C19GBA1HTT | |
| SCHEMBL7767518 | 0.71 | CRBN (0.41) | EHMT2ALDH1A1LMNAPSMD14GPR55 | |
| SCHEMBL7765772 | 0.71 | SDCBP (0.38) | EHMT2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7761783 | 0.69 | LMNA (0.46) | EHMT2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7766827 | 0.69 | CYP2C19 (0.39) | ALDH1A1LMNACYP2C19GBA1HTT | |
| SCHEMBL7766819 | 0.68 | MEN1 (0.36) | EHMT2ALDH1A1KMT2AMEN1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |