SCHEMBL7766936

SCHEMBL7766936

N#CC(C(N)=O)=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
KMT2A Q03164 2/20 0.49
CA12 O43570 1/20 0.49
USP2 O75604 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
LMNA P02545 1/20 0.49
BCHE P06276 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
HSD11B1 P28845 1/20 0.46
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659089 0.86 KDM4E (0.50) KDM4EKMT2ACA12USP2CA1
SCHEMBL8634503 0.85 KDM4E (0.49) KDM4EKMT2ACA12USP2CA1
SCHEMBL8662941 0.85 CYP1A2 (0.41) KDM4EKMT2ACA12USP2CA1
SCHEMBL8600148 0.82 HSD11B1 (0.57) KDM4EKMT2ACA12USP2CA1
SCHEMBL8410384 0.76 MEN1 (0.45) KDM4EKMT2ALMNAHSD11B1ALDH1A1
SCHEMBL2744207 0.75 HSD11B1 (0.43) KDM4EKMT2ACA12USP2CA1
SCHEMBL7998459 0.74 CA1 (0.38) KDM4EKMT2ACA12USP2CA1
Saccharin SCHEMBL28167143 0.74 CA12 (0.81) KDM4EKMT2ACA12USP2CA1
SCHEMBL27047101 0.73 KDM4E (0.57) KDM4EKMT2ACA12USP2CA1
SCHEMBL8014575 0.73 HSD11B1 (0.38) KDM4EKMT2ACA12USP2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109071-A1 2-(1,2-benzisothiazol-3(2h)-ylidene 1,1-dioxide)acetamides negative charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2001-06-20 EP claimed
US-6184387-B1 2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)acetamides negative charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY 2001-02-06 US claimed
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US claimed
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed
US-5821024-A POLYESTER BINDER OF A DICARBOXYLIC ACID AND A POLYOL BLEND OF ETHERIFIED DIPHENOLS EASTMAN KODAK COMPANY (US) 1998-10-13 US disclosed
US-5723249-A (1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide) cyanoacetate charge-control agents for electrostatographic toners EASTMAN KODAK COMPANY (US) 1998-03-03 US disclosed
US-5719000-A CHARGE CONTROL AGENTS EASTMAN KODAK COMPANY (US) 1998-02-17 US disclosed
US-5719001-A IMPROVED CHARGING, DISCOLORATION INHIBITION, IMAGE QUALITY EASTMAN KODAK COMPANY (US) 1998-02-17 US disclosed
US-5716749-A RAPIDLY CHARGING TONERS WHICH MAINTAIN CHARGES FOR EXTENDED TIMES EASTMAN KODAK COMPANY (US) 1998-02-10 US disclosed