SCHEMBL8410384

SCHEMBL8410384

N#CC(C(=O)NCc1ccccc1)=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 2/20 0.45
PLIN1 O60240 1/20 0.45
PLIN5 Q00G26 1/20 0.45
ABHD5 Q8WTS1 1/20 0.45
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HPGD P15428 2/20 0.43
FBP1 P09467 1/20 0.43
MCL1 Q07820 2/20 0.42
MAPK1 P28482 1/20 0.41
HSD11B1 P28845 1/20 0.41
GAA P10253 1/20 0.41
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659089 0.80 KDM4E (0.50) KMT2AALDH1A1KDM4EMAPTLMNA
SCHEMBL11383445 0.78 LMNA (0.47) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL8652270 0.78 KMT2A (0.36) MEN1KMT2AALDH1A1KDM4ELMNA
SCHEMBL2744207 0.77 HSD11B1 (0.43) KMT2AALDH1A1KDM4EMAPTLMNA
SCHEMBL8600148 0.77 HSD11B1 (0.57) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL7766936 0.76 KDM4E (0.49) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL8634503 0.76 KDM4E (0.49) KMT2AALDH1A1KDM4EMAPTLMNA
SCHEMBL8014575 0.72 HSD11B1 (0.38) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL7998848 0.72 HSD11B1 (0.38) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL7998459 0.71 CA1 (0.38) KMT2AALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922499-A NEGATIVELY CHARGING TONERS WITH GOOD CHARGING CHARACTERISTICS AND POLYESTER BINDERS EASTMAN KODAK COMPANY (US) 1999-07-13 US disclosed