SCHEMBL8634503

SCHEMBL8634503

N#CC(C([NH])=O)=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
CA12 O43570 1/20 0.49
USP2 O75604 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
LMNA P02545 1/20 0.49
BCHE P06276 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA5A P35218 1/20 0.49
CA7 P43166 1/20 0.49
KMT2A Q03164 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
HSD11B1 P28845 1/20 0.46
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
PTGES O14684 2/20 0.39
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659089 0.86 KDM4E (0.50) KDM4ECA12USP2CA1CA2
SCHEMBL7766936 0.85 KDM4E (0.49) KDM4ECA12USP2CA1CA2
SCHEMBL8600148 0.82 HSD11B1 (0.57) KDM4ECA12USP2CA1CA2
SCHEMBL8410384 0.76 MEN1 (0.45) KDM4ELMNAKMT2AHSD11B1ALDH1A1
SCHEMBL2744207 0.75 HSD11B1 (0.43) KDM4ECA12USP2CA1CA2
SCHEMBL27047101 0.73 KDM4E (0.57) KDM4ECA12USP2CA1CA2
SCHEMBL8014575 0.73 HSD11B1 (0.38) KDM4ECA12USP2CA1CA2
SCHEMBL7998848 0.73 HSD11B1 (0.38) KDM4ECA12USP2CA1CA2
Saccharin SCHEMBL29109712 0.72 CA12 (0.79) KDM4ECA12USP2CA1CA2
SCHEMBL7998786 0.70 HSD11B1 (0.36) KDM4ECA12USP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739235-A CHARGE CONTROL AGENTS FOR ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1998-04-14 US claimed
US-5739235-A CHARGE CONTROL AGENTS FOR ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1998-04-14 US disclosed