SCHEMBL7767129

SCHEMBL7767129

CC(C)(c1ccc(OCC=O)cc1)c1ccc(OCC=O)cc1.O=C(O)c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
NR4A2 P43354 1/20 0.47
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HIF1A Q16665 1/20 0.42
EPAS1 Q99814 1/20 0.42
CYP1A2 P05177 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PTPN1 P18031 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 2/20 0.41
GPBAR1 Q8TDU6 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263140 0.82 ALDH1A1 (0.47) KDM4EALDH1A1SMN1; SMN2HIF1ACYP1A2
SCHEMBL7771388 0.80 ALDH1A1 (0.49) KDM4EALDH1A1TP53TSHRPOLB
SCHEMBL148637 0.79 PKM (0.58) RXRARXRBNR4A2ALDH1A1SMN1; SMN2
SCHEMBL12214813 0.76 SMN1; SMN2 (0.54) KDM4EALDH1A1SMN1; SMN2POLBGAA
SCHEMBL13123723 0.75 RXRA (0.59) KDM4ERXRARXRBNR4A2SMN1; SMN2
SCHEMBL1822846 0.72 SMN1; SMN2 (0.55) KDM4ERXRARXRBNR4A2ALDH1A1
SCHEMBL19315946 0.72 L3MBTL1 (0.40) RXRARXRBNR4A2SMN1; SMN2NPC1
SCHEMBL18073444 0.72 RXRA (0.49) KDM4ERXRARXRBNR4A2ALDH1A1
SCHEMBL1634704 0.71 PARP15 (0.58) RXRARXRBNR4A2SMN1; SMN2HPGD
SCHEMBL263623 0.71 PTPN1 (0.58) KDM4ERXRARXRBNR4A2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0843210-B1 Base film for photographic films TEIJIN LTD (JP) 2001-07-25 EP disclosed
US-6165701-A Base film for photographic films TEIJIN LIMITED (JP) 2000-12-26 US disclosed
EP-0843210-A1 Base film for photographic films TEIJIN LIMITED (JP) 1998-05-20 EP disclosed