Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768105 | 0.92 | PTGES (0.34) | KDM4EPOLBTHRATHRBPDE4B | |
| SCHEMBL7767737 | 0.85 | ADRB2 (0.38) | KDM4EPOLBADRB2ADRB1ADRB3 | |
| SCHEMBL7769584 | 0.82 | LTA4H (0.35) | KDM4EPOLBTHRATHRB | |
| SCHEMBL7768123 | 0.82 | KDM4E (0.37) | KDM4EADRB3 | |
| SCHEMBL7769440 | 0.81 | LSS (0.45) | KDM4ETHRATHRB | |
| SCHEMBL7684026 | 0.81 | LSS (0.45) | KDM4ETHRATHRB | |
| SCHEMBL7684020 | 0.81 | LSS (0.45) | KDM4ETHRATHRB | |
| SCHEMBL7684015 | 0.81 | LSS (0.45) | KDM4ETHRATHRB | |
| SCHEMBL7772100 | 0.81 | KDM4E (0.33) | KDM4EPOLBPDE4BBRD4 | |
| SCHEMBL7769001 | 0.80 | THRA (0.39) | KDM4ETHRATHRBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |