Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771932 | 0.82 | F2 (0.42) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7773566 | 0.77 | MAPT (0.44) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7771927 | 0.76 | KDM4E (0.44) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7771919 | 0.74 | POLB (0.39) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7772080 | 0.73 | ALDH1A1 (0.38) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7772064 | 0.73 | FPR1 (0.39) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7772056 | 0.73 | PDE4B (0.41) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7767875 | 0.72 | KDM4E (0.43) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7771637 | 0.72 | SMN1; SMN2 (0.41) | POLBHTTMAPTALDH1A1KDM4E | |
| SCHEMBL7775674 | 0.72 | TP53 (0.48) | POLBHTTMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |