Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17211607 | 0.82 | LMNA (0.46) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL8933210 | 0.76 | LMNA (0.49) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL35507 | 0.75 | TSHR (0.63) | LMNATSHR | |
| SCHEMBL22168536 | 0.74 | THRB (0.40) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL8230945 | 0.74 | LMNA (0.53) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL8667841 | 0.74 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2 | |
| SCHEMBL23230272 | 0.73 | LMNA (0.38) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL5693403 | 0.72 | TSHR (0.55) | LMNATSHR | |
| SCHEMBL20204440 | 0.72 | THRB (0.40) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL16803284 | 0.72 | TSHR (0.63) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685454-B2 | X-ray opaque dental materials | IVOCLAR VIVADENT AG (LI) | 2001-06-27 | — | — | EP | disclosed |
| US-5780668-A | A CURABLE MONOMER OF A (MONO-, DI- OR TRIACRYLOYLOXY-SUBSTITUTED ALKYLENEAMIDO OR OXYCARBONYL-) -TRIODOBENZENES; REPLACES FILLERS IN CROWNS, BRIDGES ETC.; UV RESISTANCE; STABILITY | IVOCLAR AG (LI) | 1998-07-14 | — | — | US | disclosed |
| EP-0685454-B1 | X-ray opaque dental materials | IVOCLAR AG (LI) | 1997-10-15 | — | — | EP | disclosed |
| EP-0685454-A1 | X-ray opaque dental materials | IVOCLAR AG (LI) | 1995-12-06 | — | — | EP | disclosed |