Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405977 | 0.89 | GPR52 (0.41) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL9214298 | 0.85 | SLC6A2 (0.44) | SLC6A2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL9848958 | 0.80 | MAOB (0.46) | SLC6A2L3MBTL1SIGMAR1MAOAMAOB | |
| SCHEMBL5570918 | 0.78 | L3MBTL1 (0.40) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL6049171 | 0.76 | CHRM2 (0.42) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL5610556 | 0.75 | FAAH (0.44) | ADRA1ASLC6A3L3MBTL1SIGMAR1MAOA | |
| SCHEMBL5795177 | 0.72 | CHRM2 (0.48) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL430012 | 0.71 | SIGMAR1 (0.54) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL19031840 | 0.71 | EPHX2 (0.52) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14638684 | 0.71 | KCNH2 (0.47) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105112-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009108-A2 | COMPOSITIONS AND USES FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |