Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765648 | 0.84 | AHR (0.41) | AHRMAPK1KDM4EATMCYP1A2 | |
| SCHEMBL7769523 | 0.76 | DRD2 (0.44) | AHRMAPK1KDM4EATMCYP1A2 | |
| SCHEMBL5953444 | 0.75 | HTR1A (0.34) | AHRHPGDSMN1; SMN2 | |
| SCHEMBL5953552 | 0.74 | PYCR1 (0.49) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9054156 | 0.74 | LIMK1 (0.35) | AHRHPGDSMN1; SMN2 | |
| SCHEMBL4043114 | 0.70 | LMNA (0.46) | AHRMAPK1KDM4EATMRAB9A | |
| SCHEMBL7770728 | 0.68 | DRD2 (0.43) | AHRMAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7769088 | 0.67 | AHR (0.37) | AHRMAPK1KDM4EATMP2RY6 | |
| SCHEMBL10734044 | 0.67 | MAPK1 (0.43) | AHRMAPK1KDM4EATMCYP1A2 | |
| SCHEMBL7769548 | 0.65 | CYP1A2 (0.37) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726265-B1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | NOVARTIS AG (CH) | 2001-07-25 | — | — | EP | disclosed |
| EP-0726265-A1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | CIBA-GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |